Simon is a native of County Wicklow and has been involved in the community all his life.
Simon first became involved in politics through his work as a disability advocate. Before entering politics, Simon established the Wicklow Triple A Alliance, a charity to support children and families affected by Autism. He was first elected to Dáil Éireann in the 2011 General Election and was the youngest member of the 31st Dáil. During that Dáil term, Simon served as a member of the Public Accounts Committee, Oireachtas Committee on Finance, Public Expenditure and Reform, Secretary of the Fine Gael Parliamentary Party and Co-Convenor of the Oireachtas Cross Party Group on Mental Health, before being appointed in July 2014 as Minister of State in the Departments of Finance, Public Expenditure and Reform and the Department of the Taoiseach with Special Responsibility for OPW, Public Procurement and International Banking (including IFSC).
Simon was re-elected as TD for Wicklow and East Carlow in the February 2016 General Election and subsequently appointed Minister for Health.